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Rac-Modipafant

Cat. No. M9659

All AbMole products are for research use only, cannot be used for human consumption.

Rac-Modipafant Structure
Synonym:

Modipafant racemate; UK-74505

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Quality Control & Documentation
Biological Activity

Rac-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist.

Chemical Information
Molecular Weight 605.09
Formula C34H29ClN6O3
CAS Number 122956-68-7
Solubility (25°C) Soluble in HCl 0.1%
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ana T Guerrero, et al. Naunyn Schmiedebergs Arch Pharmacol. The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia

[2] Danielle G Souza, et al. Proc Natl Acad Sci U S A. Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection

[3] M J Parry, et al. J Lipid Mediat Cell Signal. Pharmacological profile of UK-74,505, a novel and selective PAF antagonist with potent and prolonged oral activity

[4] V A Alabaster, et al. Agents Actions Suppl. UK-74,505, a novel and selective PAF antagonist, exhibits potent and long lasting activity in vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: Rac-Modipafant, Modipafant racemate; UK-74505 supplier, Platelet-activating Factor Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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