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(R)-MG-132(Z-LEu-LEu-Al) is a cellular permeable proteasome and Calpain inhibitor with IC50 of 100 nM and 1.2 μM, respectively.
| Molecular Weight | 475.62 |
| Formula | C26H41N3O5 |
| CAS Number | 1211877-36-9 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | -20°C |
| Related Proteasome Products |
|---|
| Bortezomib (PS-341)
Bortezomib (PS-341) is a highly selective proteasome inhibitor with a ki value of 6nM. |
| CTP-518
CTP-518 is a novel HIV protease inhibitor. CTP-518 has the potential to be the first HIV protease inhibitor toeliminate the need to co-dose with a boosting agent. |
| ITMN-191
ITMN-191 (Danoprevir, RG7227) is a potent and orally active inhibitor of hepatitis C virus (HCV) NS3/4A serine protease with an IC50 of 1.6 nM. |
| MG132
MG132 is a specific and potent cell-permeable proteasome inhibitor (IC50 = 100 nM, Ki = 4 nM). MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132 is also a calpain inhibitor with IC50 of 1.2 μM. |
| IU1
IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. |
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