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Quilizumab

Cat. No. M24581

All AbMole products are for research use only, cannot be used for human consumption.

Quilizumab Structure
Synonym:

Anti-Human NGcGM3 Recombinant Antibody

Price and Availability

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Quality Control & Documentation
Biological Activity

Quilizumab (Anti-Human NGcGM3 Recombinant Antibody) is a humanized IgG1κ monoclonal antibody. Quilizumab targets the M1-prime segment of membrane-expressed IgE, leading to depletion of IgE-switched and memory B cells. Quilizumab has the potantial for the asthma research.

Chemical Information
CAS Number 1228538-47-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Alessandro Fiocchi, et al. Clin Exp Allergy. The use of biologics in food allergy

[2] Bettina Wedi, et al. Immunotargets Ther. Anti-IgE for the Treatment of Chronic Urticaria

[3] Jeffrey M Harris, et al. J Allergy Clin Immunol. A randomized trial of quilizumab in adults with refractory chronic spontaneous urticaria

[4] Jeffrey M Harris, et al. Respir Res. A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma

[5] Gail M Gauvreau, et al. Sci Transl Med. Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production

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Keywords: Quilizumab, Anti-Human NGcGM3 Recombinant Antibody supplier, Apoptosis, inhibitors, activators

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