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QAQ 

Cat. No. M27938

All AbMole products are for research use only, cannot be used for human consumption.

QAQ  Structure

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Quality Control & Documentation
Biological Activity

QAQ dichloride dichloride, a photoswitchable voltage-gated Nav and Kv channels blocker, blocks channels in its trans form (of the azobenzene photoswitch), but not in its cis form. QAQ dichloride dichloride is membrane-impermeant and only infiltrates pain-sensing neurons that express endogenous import channels. QAQ dichloride dichloride acts as a light-sensitive analgesic and can be used for studying of signaling mechanisms in acute and chronic pain.

Chemical Information
Molecular Weight 496.69
Formula C28H44N6O22+
CAS Number 1204416-85-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Anna Kádková, et al. Neuroscience. The SNAP-25 Protein Family

[2] Alexandre Mourot, et al. Br J Pharmacol. Understanding and improving photo-control of ion channels in nociceptors with azobenzene photo-switches

[3] Rebecca Groynom, et al. J Drug Target. Controlled release of photoswitch drυgs by degradable polymer microspheres

[4] Alexandre Mourot, et al. Nat Methods. Rapid optical control of nociception with an ion-channel photoswitch

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  Catalog
Abmole Inhibitor Catalog




Keywords: QAQ  supplier, Sodium Channel, inhibitors, activators

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