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Pyrazoloacridine (NSC 366140) has anticancer activity, inhibiting the activity of topoisomerases 1 and 2 (topoisomerases 1 and 2). Pyrazoloacridine (NSC 366140) on K562 in myeloid leukemia cells IC50 The value is 1.25 μM (24 h).
| Molecular Weight | 367.4 |
| Formula | C19H21N5O3 |
| CAS Number | 99009-20-8 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] A A Adjei. Invest New Drugs. Current status of pyrazoloacridine as an anticancer agent
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