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Pyrazofurin

Cat. No. M8555

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Pyrazofurin Structure
Size Price Availability Quantity
1mg USD 170 In stock
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Quality Control & Documentation
Biological Activity

Pyrazofurin is an orotidine-5’-monophosphate decarboxylase (ODCase, OMP decarboxylase) inhibitor that exhibit potent antiviral, anti-malarial and anti-trypanosomes activities.

Chemical Information
Molecular Weight 259.22
Formula C9H13N3O6
CAS Number 30868-30-5
Form Solid
Solubility (25°C) Water: 5 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jakob Bouton, et al. Sydnone Ribosides as a Platform for the Synthesis of Pyrazole C-Nucleosides: A Unified Synthesis of Formycin B and Pyrazofurin

[2] Meng Zhang, et al. Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds

[3] Daan Ren, et al. Identification of the C-Glycoside Synthases during Biosynthesis of the Pyrazole-C-Nucleosides Formycin and Pyrazofurin

[4] Erik De Clercq. C-Nucleosides To Be Revisited

[5] C R Petrie 3rd, et al. Synthesis and biological activity of certain nucleoside and nucleotide derivatives of pyrazofurin

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Keywords: Pyrazofurin supplier, DNA/RNA Synthesis, inhibitors, activators

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