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PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors.
| Molecular Weight | 432.47 |
| Formula | C25H24N2O5 |
| CAS Number | 1560894-05-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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