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PXS-5120A 

Cat. No. M29269

All AbMole products are for research use only, cannot be used for human consumption.

PXS-5120A  Structure
Size Price Availability Quantity
5mg USD 620 In stock
10mg USD 820 In stock
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Quality Control & Documentation
Biological Activity

PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8).

Chemical Information
Molecular Weight 481.97
Formula C22H25ClFN3O4S
CAS Number 2125955-70-4
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage 4°C, dry, sealed
References

[1] Yordanos F I Setargew, et al. Cancers (Basel). Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours

[2] Alison D Findlay, et al. J Med Chem. Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3

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  Catalog
Abmole Inhibitor Catalog




Keywords: PXS-5120A  supplier, Monoamine Oxidase, inhibitors, activators

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