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Purpurogallin

Cat. No. M58176

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Purpurogallin Structure

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Quality Control & Documentation
Biological Activity

Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 µM. Purpurogallin has antioxidant and anti-inflammatory effects. Purpurogallin (50 or 100 µM; 7 or 25 hours; BV2 murine microglial cells) treatment attenuates the production of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by suppressing their mRNA and protein expression in LPS-stimulated BV2 microglial cells.

Chemical Information
Molecular Weight 220.18
Formula C11H8O5
CAS Number 569-77-7
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage -20°C, sealed
Related Xanthine Oxidase Products
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Febuxostat (TEI-6720) is a non-purine selective xanthine oxidase inhibitor with IC50 of 114 -210 nM.

Allopurinol

Allopurinol is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

Allopurinol Sodium

Allopurinol Sodium is a xanthine oxidase inhibitor and a structural isomer of hypoxanthine with an IC50 of 7.82 ± 0.12 μM, which inhibits the conversion of xanthine to uric acid and increases the reuse of hypoxanthine and xanthine in nucleic acid synthesis, thereby reducing serum and urinary uric acid levels, and can be used in gout-related studies.

Topiroxostat

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Broussoflavonol F

Broussoflavonol F has xanthine oxidase inhibitory activity.

  Catalog
Abmole Inhibitor Catalog




Keywords: Purpurogallin supplier, Xanthine Oxidase, inhibitors, activators

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