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Psicofuranine

Cat. No. M15059

All AbMole products are for research use only, cannot be used for human consumption.

Psicofuranine  Structure
Size Price Availability
1mg USD 375 3-4 Weeks
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Quality Control & Documentation
Biological Activity

Psicofuramine is a nucleoside antibiotic produced by the hygroscopic Streptomyces strain Bitter fungus. It has antifungal activity against Gram-positive bacteria and mycobacterium, and has antifungal activity against Walker cancer 256 in rats and Ca755 in mice.

Chemical Information
Molecular Weight 297.27
Formula C11H15N5O5
CAS Number 1874-54-0
Form Solid
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] L J HANKA. J Bacteriol. Mechanism of action of psicofuranine

[2] T SUGIMORI, et al. J Am Chem Soc. THE BIOSYNTHESIS OF PSICOFURANINE

[3] S UDAKA, et al. J Biol Chem. INHIBITION OF PARENTAL AND MUTANT XANTHOSINE 5'-PHOSPHATE AMINASES BY PSICOFURANINE

[4] L SLECHTA. Biochem Pharmacol. Studies on the mode of action of psicofuranine

[5] C E Rohlman, et al. J Bacteriol. Role of purine biosynthetic intermediates in response to folate stress in Escherichia coli

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