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PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively.
| Molecular Weight | 588.09 |
| Formula | C10H12FN2Na4O14P3 |
| CAS Number | 1621884-22-7 |
| Form | Solid |
| Solubility (25°C) | Water ≥ 100 mg/mL |
| Storage | -20°C, dry, sealed |
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