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Pseudolaric-Acid-B

Cat. No. M4723

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Pseudolaric-Acid-B Structure
Size Price Availability Quantity
1mg USD 30 In stock
5mg USD 60 In stock
10mg USD 90 In stock
20mg USD 130 In stock
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Quality Control & Documentation
Biological Activity

Pseudolaric-Acid-B is a diterpene isolated from the root of Pseudolarix kaempferi Gorden (pinaceae), which shows immunosuppressive activity on T lymphocytes. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest. Pseudolaric Acid B induces autophagy.

Chemical Information
Molecular Weight 432.46
Formula C23H28O8
CAS Number 82508-31-4
Solubility (25°C) DMSO ≥ 10 mg/mL
Storage 2-8°C, dry, protect from light, sealed
References

[1] Fang-Fang Yu, et al. Pseudolaric Acid B Attenuates High Salt Intake-Induced Hypertensive Left Ventricular Remodeling by Modulating Monocyte/Macrophage Phenotypes

[2] Jiansen Lu, et al. Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF-κB signalling pathway

[3] Su-Fen Wei, et al. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma

[4] Chunyu Liu, et al. Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells

[5] Zongqi Wang, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT

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