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ProTx II TFA is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes.
Adv Sci (Weinh). 2024 Sep 09.
Optimizing Nav1.7-Targeted Analgesics: Revealing Off-Target Effects of Spider Venom-Derived Peptide Toxins and Engineering Strategies for Improvement
ProTx II TFA purchased from AbMole
| Formula | C168H250N46O41S8.xC2HF3O2 |
| CAS Number | 484598-36-9 (free base) |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL (Need ultrasonic) |
| Storage | Store at ≤ -20°C, protect from light, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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