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Protoporphyrin IX is the final intermediate in the heme biosynthetic pathway. Protoporphyrin IX acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma.
| Molecular Weight | 562.66 |
| Formula | C34H34N4O4 |
| CAS Number | 553-12-8 |
| Solubility (25°C) | DMSO 2 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
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