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PROTAC IRAK4 degrader-8 is a PROTAC targeting to IRAK4 (IC50=15.5 nM).
| Molecular Weight | 874.38 |
| Formula | C43H50ClF2N11O5 |
| CAS Number | 2911615-06-8 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Zi Liu et al. Mol Biomed. An overview of PROTACs: a promising drug discovery paradigm
[2] Tingting Yao et al. Int J Mol Sci. Recent Advances in PROTACs for Drug Targeted Protein Research
[3] Robert B Kargbo. ACS Med Chem Lett. PROTAC Degradation of IRAK4 for the Treatment of Cancer
[5] Joao Nunes et al. ACS Med Chem Lett. Targeting IRAK4 for Degradation with PROTACs
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| Zabedosertib
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