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PROTAC α-synuclein degrader 5

Cat. No. M43429

All AbMole products are for research use only, cannot be used for human consumption.

PROTAC α-synuclein degrader 5 Structure

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Quality Control & Documentation
Biological Activity

PROTAC α-synuclein degrader 5 is a highly selective small-molecule degraders (PROTAC) of α-synuclein aggregates, with an DC50 of 7.51 μM and the highest degradation rate Dmax of 89%.

Chemical Information
Molecular Weight 767.78
Formula C39H41N7O10
CAS Number 2781922-42-5
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tianzhi Wen et al. Molecules. Design, Synthesis and Biological Evaluation of α-Synuclein Proteolysis-Targeting Chimeras

[2] Martina Pedrini et al. Pharmaceutics. Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation

[3] Yves Leestemaker et al. Cell Chem Biol. Proteasome Activation by Small Molecules

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Keywords: PROTAC α-synuclein degrader 5 supplier, PROTAC, inhibitors, activators

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