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Prostaglandin F2α (Dinoprost) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist.
Prostaglandin F2α (1 μM; 24 h) significantly increased the apoptotic rate in Goat luteal cells. The expression of GRP78 and UPR sensors including cleaved ATF6, phosphorylated-EIF2S1, EIF2S1, ATF4, phosphorylated-IRE1, autophagy-related protein LC3-II, and pro-apoptosis factor cleaved Caspase3 increased significantly in the cells.
| Molecular Weight | 354.48 |
| Formula | C20H34O5 |
| CAS Number | 551-11-1 |
| Form | Melting point 25-35°C |
| Solubility (25°C) | DMSO 90 mg/mL Water 90 mg/mL |
| Storage | Store at -20°C |
| Related Prostaglandin Receptor Products |
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| Ethamsylate
Ethamsylate is a haemostatic compound, which inhibits biosynthesis and action of prostaglandins, and increases capillary endothelial resistance as and platelet adhesion. |
| Tafluprost
Tafluprost is a fluorinated analog of prostaglandin F2-alpha and a PGF2alpha agonist that may be used in glaucoma-related studies. |
| Terutroban
Terutroban is a selective antagonist of the thromboxane receptor. |
| Prostaglandin E1
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, which induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases. |
| Latanoprost
Latanoprost is a prostaglandin F2α analog as well as a prostaglandin-like selective FP receptor agonist with lipophilic and corneal penetrating properties. In addition, Latanoprost also increases ocular fluid outflow, thereby reducing intraocular pressure, and may be used in studies related to glaucoma. |
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