All AbMole products are for research use only, cannot be used for human consumption.
In vitro: PGE2 shows inhibition of IL 2 production in the mixture of irradiated and nonirradiated T lymphocytes. PGE2 (0.1-10 μM) dose-dependently inhibits the production of IL 2. PGE2 acts during the inductive phase of activation of suppressor cells. Preincubation of T lymphocytes with PGE2 induces cells that suppress IL 2 production and PHA proliferation.
In vivo: PGE2 (0.3 μg/k, i.p.) significantly reduces the number of peritoneab macrophages undergoing phagocytosis of the methacrybate microbeads in rats. PGE2 (0.1 mg/min, i.a.) increases renal blood flow. PGE2 produces a biphasic change in renal vascular resistance, vasodilatation starts at 0.01 mg/min and is maximal at about 3 mg/min, while at the highest dose used (20 mg/min) PGE2 induces renal vasoconstriction.
Patent. CN119639678A 2025 Mar 18.
Patent. CN119639678A
Prostaglandin E2 purchased from AbMole
Cell Metab. 2024 Oct 18.
Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex
Prostaglandin E2 purchased from AbMole
Cancer Lett. 2024 Oct 02;605:217284.
Exploring epigenetic dynamics unveils a super-enhancer-mediated NDRG1-β-catenin axis in modulating gemcitabine resistance in pancreatic cancer
Prostaglandin E2 purchased from AbMole
Toxicol Appl Pharmacol. 2024 Sep 24.
Human trophoblast organoids for improved prediction of placental ABC transporter-mediated drug transport
Prostaglandin E2 purchased from AbMole
Biochem Biophys Res Commun. 2023 Nov 12;681:55-61.
Antinociceptive effect of gelsenicine, principal toxic alkaloids of gelsemium, on prostaglandin E2-induced hyperalgesia in mice: Comparison with gelsemine and koumine
Prostaglandin E2 purchased from AbMole
Cell Death Dis. 2022 Apr 5;13(4):303.
KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response
Prostaglandin E2 purchased from AbMole
| Cell Experiment | |
|---|---|
| Cell lines | ovulatory follicles |
| Preparation method | All cells and tissues were obtained after ovarian stimulation before (0 h) and 12, 24, or 36 h after administration of an ovulatory dose of hCG. |
| Concentrations | |
| Incubation time | 12, 24, or 36 h |
| Animal Experiment | |
|---|---|
| Animal models | male dogs |
| Formulation | |
| Dosages | 0.1 mg/kg |
| Administration | oral |
| Molecular Weight | 352.47 |
| Formula | C20H32O5 |
| CAS Number | 363-24-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| Terutroban
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| Latanoprost
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