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Proguanil is a prophylactic antimalarial agent. Proguanil inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
| Molecular Weight | 253.73 |
| Formula | C11H16ClN5 |
| CAS Number | 500-92-5 |
| Solubility (25°C) | DMSO 51 mg/mL Water 1 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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