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Procainamide is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1). Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias.
| Molecular Weight | 235.33 |
| CAS Number | 51-06-9 |
| Storage | 2-8°C, protect from light |
[2] K A Ellenbogen, et al. Heart Dis Stroke. Procainamide: a perspective on its value and danger
[3] C Ribeiro, et al. Eur Heart J. Procainamide and disopyramide
[4] E Karlsson. Clin Pharmacokinet. Clinical pharmacokinetics of procainamide
| Related DNA Methyltransferase Products |
|---|
| Decitabine
Decitabine (5-Aza-2'-deoxycytidine) is a potent inhibitor of DNA methylation for the treatment of myelodysplastic syndromes. |
| RG108
RG108 is a novel small-molecule inhibitors of DNA methyltransferases with IC50 of 115 nM. |
| Lomeguatrib
Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM. |
| SGI-1027
SGI-1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B |
| SGI-110
SGI-110 (S-110) is a stable and potent inhibitor for DNA methylation, inhibits DNMT1 when SGI-110 is activated by phosphorylation and incorporated into DNA. |
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