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Pridopidine is a dopamine (DA) stabilizer that acts as a low-affinity dopamine D2 receptor (D2R) antagonist. Pridopidine high affinity acts on sigma 1 receptor (S1R),Ki Values of 70 to 80 nM are approximately 100 times higher than their affinity for D2R.
| Molecular Weight | 281.41 |
| Formula | C15H23NO2S |
| CAS Number | 346688-38-8 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Magdalena Jabłońska, et al. Rev Neurosci. Pridopidine in the treatment of Huntington's disease
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