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Pregnenolone monosulfate

Cat. No. M14560

All AbMole products are for research use only, cannot be used for human consumption.

Pregnenolone monosulfate Structure
Synonym:

3β-Hydroxy-5-pregnen-20-one monosulfate

Size Price Availability Quantity
5mg USD 58 In stock
10mg USD 95 In stock
25mg USD 160 In stock
50mg USD 240 In stock
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Quality Control & Documentation
Biological Activity

Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication. Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels.

Chemical Information
Molecular Weight 396.54
Formula C21H32O5S
CAS Number 1247-64-9
Solubility (25°C) DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Amneh H Tarkhan, et al. Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels

[2] Gary Grosser, et al. Transport of steroid 3-sulfates and steroid 17-sulfates by the sodium-dependent organic anion transporter SOAT (SLC10A6)

[3] G H Corsan, et al. Origin of deoxycorticosterone sulfate (DOC-SO4) in plasma of pregnant women: pregnenolone-3,21-disulfate is a placental precursor of DOC-SO4

[4] T Wong, et al. Identification of the steroids in neonatal plasma that interfere with 17 alpha-hydroxyprogesterone radioimmunoassays

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Keywords: Pregnenolone monosulfate, 3β-Hydroxy-5-pregnen-20-one monosulfate supplier, Cannabinoid, inhibitors, activators

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