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PRE-084 is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
| Molecular Weight | 317.42 |
| Formula | C19H27NO3 |
| CAS Number | 138847-85-5 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] C V Haritha, et al. Tissue Cell. PRE-084 ameliorates adenine-induced renal fibrosis in rats
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