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Pradimicin A 

Cat. No. M27886

All AbMole products are for research use only, cannot be used for human consumption.

Pradimicin A  Structure

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Quality Control & Documentation
Biological Activity

Pradimicin A (PRM-A) is a potent antifungal agent, with an MIC of 4 μg/mL against Candida rugosa. Pradimicin A has antiviral activities against CoV, HIV and other enveloped viruses. Pradimicin A shows aggregation property, and can recognize d-Man in the presence of Ca2+ ion.

Chemical Information
Molecular Weight 840.78
Formula C40H44N2O18
CAS Number 117704-65-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yu Nakagawa, et al. J Nat Prod. A Pradimicin-Based Staining Dye for Glycoprotein Detection

[2] Yu Nakagawa, et al. Bioorg Med Chem Lett. Pradimicin A, a D-mannose-binding antibiotic, binds pyranosides of L-fucose and L-galactose in a calcium-sensitive manner

[3] Kandy L Napan, et al. Bioorg Med Chem Lett. A key cytochrome P450 hydroxylase in pradimicin biosynthesis

[4] Jan Balzarini, et al. J Virol. Pradimicin A, a carbohydrate-binding nonpeptidic lead compound for treatment of infections with viruses with highly glycosylated envelopes, such as human immunodeficiency virus

[5] A Tanabe-Tochikura, et al. Virology. Pradimicin A inhibition of human immunodeficiency virus: attenuation by mannan

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