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PQ1 succinate

Cat. No. M8341

All AbMole products are for research use only, cannot be used for human consumption.

PQ1 succinate Structure

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Quality Control & Documentation
Biological Activity

PQ1 binds tightly to connexin 43 and activates intracellular gap junctions. Treatment of the breast cancer cell line T47D with 200 nM PQ1 induces a 30% increase in gap junctional intercellularcommunication (GJIC) and a 90% decrease in cell growth, with no effect on normal breast epithelial cells.

Chemical Information
Molecular Weight 523.5
Formula C25H28F3N3O6
CAS Number 955995-51-4
Solubility (25°C) DMSO: 15 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Elisabeth M Perchellet, et al. Bioactivity and molecular targets of novel substituted quinolines in murine and human tumor cell lines in vitro

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Keywords: PQ1 succinate supplier, inhibitors, activators

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