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PQ-10

Cat. No. M8447

All AbMole products are for research use only, cannot be used for human consumption.

PQ-10 Structure

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Quality Control & Documentation
Biological Activity

PQ-10 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10). Apparently, PQ-10 enhances basic auditory information processing in rats. PQ-10 as other PED10 inhibitors suppresses a growth of human non-small cell lung cancer (NSCLC) cell lines.

Chemical Information
Molecular Weight 403.43
Formula C22H21N5O3
CAS Number 927691-21-2
Solubility (25°C) DMSO: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chih-Chuan Lin, et al. Hemodynamic and electromechanical effects of paraquat in rat heart

[2] Preechaya Tajai, et al. Andrographolide, an Antioxidant, Counteracts Paraquat- Induced Mutagenesis in Mammalian Cells

[3] Hong Pan, et al. Solution and rheological properties of cationic cellulose/gemini surfactant: Effect of the alkyl chain and spacer length

[4] Stephen A Ferguson, et al. Detecting Levels of Polyquaternium-10 (PQ-10) via Potentiometric Titration with Dextran Sulphate and Monitoring the Equivalence Point with a Polymeric Membrane-Based Polyion Sensor

[5] Farzaneh Fayazpour, et al. Physicochemical and transfection properties of cationic Hydroxyethylcellulose/DNA nanoparticles

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Abmole Inhibitor Catalog




Keywords: PQ-10 supplier, inhibitors, activators

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