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Polygodial

Cat. No. M7151

All AbMole products are for research use only, cannot be used for human consumption.

Polygodial Structure

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Quality Control & Documentation
Biological Activity

Polygodial is a tRPA1 channel activator (EC50 = 400 nM) that is selective against TRPV1, TRPV2, TRPV3, TRPV4 and TRPM8 channels. Acts as an analgesic via desensitization of sensory neurons. Also exhibits antifungal activity via inhibition of mitochondrial ATPase.

Chemical Information
Molecular Weight 234.33
Formula C15H22O2
CAS Number 6754-20-7
Solubility (25°C) DMSO 23.43 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Held, et al. Proc Natl Acad Sci USA. Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.

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Keywords: Polygodial supplier, inhibitors, activators

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