Free shipping on all orders over $ 500

Poloxime 

Cat. No. M28838

All AbMole products are for research use only, cannot be used for human consumption.

Poloxime  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity.

Chemical Information
Molecular Weight 179.22
Formula C10H13NO2
CAS Number 17302-61-3
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Payam Zarrintaj, et al. Acta Biomater. Poloxamer: A versatile tri-block copolymer for biomedical applications

[2] Karim A Soliman, et al. Drug Discov Today. Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications

[3] Unji Lee, et al. Xenobiotica. Pharmacokinetic alterations in poloxamer 407-induced hyperlipidemic rats

[4] Gilles Dumortier, et al. Pharm Res. A review of poloxamer 407 pharmaceutical and pharmacological characteristics

[5] Winter J Gibbs, et al. Ann Pharmacother. Purified poloxamer 188 for sickle cell vaso-occlusive crisis

Related PLK Products
BI 2536

BI 2536 is a novel, highly selective, potent dual PLK1 and BRD4 inhibitor with IC50s of 0.83 and 25 nM, respectively.

BI 6727

BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk1) with an IC50 of 0 .87 nM.

GSK461364

GSK461364 is a potent and selective small molecule inhibitor of Polo-like kinase 1 (PLK1) with a Ki of 2.2 nM.

Rigosertib sodium

Rigosertib sodium is a dual non-ATP inhibitor of polo-like kinase 1 (Plk1) and phosphoinositide 3-kinase pathways (PI3K).

GW843682X

GW 843682X is a PLK inhibitor for PLK1 and PLK3 with IC50 of 2.2 nM and 9.1 nM, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: Poloxime  supplier, PLK, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.