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PNU 96415E

Cat. No. M7150

All AbMole products are for research use only, cannot be used for human consumption.

PNU 96415E Structure

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Biological Activity

PNU 96415E is a antipsychotic compound. Displays high affinity for dopamine D4 and serotonergic 5-HT2A receptors and relatively weak affinity at D2 receptors (Ki values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D4, 5-HT2A, 5-HT1A, α1, D2, D3, D1, α2 and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats.

Chemical Information
Molecular Weight 413.36
Formula C21H25FN2O.2HCl
CAS Number 170856-41-4
Solubility (25°C) Water 4.13 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fang, et al. Brain Res. Opioid receptors (DAGO-enkephalin, dynorphin A(1-13), BAM 22P) microinjected into the rat brainstem: comparison of their antinociceptive effect and their effect on neuronal firing in the rostral ventromedial medulla.

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Keywords: PNU 96415E supplier, inhibitors, activators

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