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PMSG (Pregnant mare serum gonadotropin) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus.
| Cell Experiment | |
|---|---|
| Cell lines | The rat immortalized granulosa cells |
| Preparation method | The cells were stimulated with PMSG (0.1–30 IU/mL), and progesterone accumulation in the culture media after 24 h was determined. |
| Concentrations | 0.1–30 IU/mL |
| Incubation time | 24 h |
| Animal Experiment | |
|---|---|
| Animal models | KM mice |
| Formulation | Saline |
| Dosages | 0, 5, 7.5 and 10 IU |
| Administration | S.C. |
| CAS Number | 9002-70-4 |
| Form | Powder |
| Solubility (25°C) | Saline |
| Storage | 2-8°C, dry |
| Related Metabolite/Endogenous Metabolite Products |
|---|
| 2'-Deoxyinosine
2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability. |
| Ribitol
Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose. |
| Glycodeoxycholic Acid
Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis. |
| Glycolithocholic acid
Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC). |
| 4-Aminohippuric Acid
4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow. |
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