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(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.
| Molecular Weight | 239.67 |
| Formula | C10H12F3N · HCl |
| CAS Number | 37936-89-3 |
| Solubility (25°C) | Water: ≥10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Parthena Martin, et al. Fenfluramine acts as a positive modulator of sigma-1 receptors
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