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(+)-Corynoline

Cat. No. M4697

All AbMole products are for research use only, cannot be used for human consumption.

(+)-Corynoline Structure
Size Price Availability Quantity
5mg USD 60 In stock
10mg USD 100 In stock
20mg USD 160 In stock
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Quality Control & Documentation
Biological Activity

Corynoline is a reversible and non-competitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM. Corynoline acts as an anti-inflammatory by activating Nrf2.

Chemical Information
Molecular Weight 367.40
Formula C21H21NO5
CAS Number 18797-79-0
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ziqi Yan, et al. The phytochemical, corynoline, diminishes Aurora kinase B activity to induce mitotic defect and polyploidy

[2] Yunhao Wu, et al. Corynoline protects lipopolysaccharide-induced mastitis through regulating AKT/GSK3β/Nrf2 signaling pathway

[3] Chunyang Yi, et al. Natural product corynoline suppresses melanoma cell growth through inducing oxidative stress

[4] Bin Liu, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2

[5] Yan Liu, et al. Corynoline attenuates LPS-induced acute lung injury in mice by activating Nrf2

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Keywords: (+)-Corynoline supplier, AChR/AChE, inhibitors, activators

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