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PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis.
| Molecular Weight | 431.57 |
| Formula | C24H37N3O4 |
| CAS Number | 2408065-32-5 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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