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Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.
| Molecular Weight | 378.5 |
| Formula | C22H34O5 |
| CAS Number | 125-65-5 |
| Form | Solid |
| Solubility (25°C) | DMSO: ≥10 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Elias B Chahine, et al. Lefamulin: The First Systemic Pleuromutilin Antibiotic
[4] Michael P Veve, et al. Lefamulin: Review of a Promising Novel Pleuromutilin Antibiotic
[5] Y-Z Tang, et al. Pleuromutilin and its derivatives-the lead compounds for novel antibiotics
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