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Pleconaril is an orally bioavailable, broad-spectrum antipicorna-viral agent that binds to hydrophobic pocket in VP1 major capsid protein. Also, pleconaril delays the onset of diabetes in experimental animals infected with Ljungan virus (LV).
| Molecular Weight | 381.35 |
| Formula | C18H18F3N3O3 |
| CAS Number | 153168-05-9 |
| Solubility (25°C) | DMSO: ≥10 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Naomi R Florea, et al. Pleconaril, a novel antipicornaviral agent
[3] A Billich. Pleconaril Sanofi Synthélabo/ViroPharma
[4] J M Rogers, et al. Pleconaril. A broad spectrum antipicornaviral agent
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