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PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages.
| Molecular Weight | 367.45 |
| Formula | C23H21N5 |
| CAS Number | 1314594-23-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 125 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | 4°C, protect from light |
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