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PK-THPP

Cat. No. M7144

All AbMole products are for research use only, cannot be used for human consumption.

PK-THPP Structure

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Quality Control & Documentation
Biological Activity

PK-THPP is a potent TASK-3 channel blocker (IC50 = 35 and 300 nM for TASK-3 and TASK-1 respectively). Increases breathing rate and induces respiratory alkalosis in rats.

Chemical Information
Molecular Weight 468.59
Formula C29H32N4O2
CAS Number 1332454-07-5
Solubility (25°C) 1eq. HCl 9.37 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Njar & Brodie, et al. J Med Chem. Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer.

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Keywords: PK-THPP supplier, inhibitors, activators

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