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Pirmitegravir

Cat. No. M29421

All AbMole products are for research use only, cannot be used for human consumption.

Pirmitegravir Structure
Synonym:

STP0404

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Quality Control & Documentation
Biological Activity

Pirmitegravir is a potent and first-in-class inhibitor of allosteric integrase (ALLINI) that targets LEDGF/p75 binding site. Pirmitegravir displays picomolar IC50 in human PBMCs with a >24,000 therapeutic index against HIV-1. Pirmitegravir harbors outstanding anti-virus and safety properties.

Chemical Information
Molecular Weight 495.01
Formula C27H31ClN4O3
CAS Number 2245231-10-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Matthew R Singer, et al. mBio. The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function

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Keywords: Pirmitegravir, STP0404 supplier, inhibitors, activators

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