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Piribedil hydrochloride

Cat. No. M30605

All AbMole products are for research use only, cannot be used for human consumption.

Piribedil hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Piribedil hydrochloride is a potent and orally active dopamine D2 and dopamine D3 agonist. Piribedil hydrochloride is also a α2-adrenoceptors antagonist. Piribedil hydrochloride can inhibit MLL1 methyltransferase activity (EC50: 0.18 μM). Piribedil hydrochloride has the potential for the research of parkinson's disease, circulatory disorders, cancers.

Chemical Information
Molecular Weight 334.8
Formula C16H19ClN4O2
CAS Number 78213-63-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Chandra Teja Uppuluri, et al. Int J Pharm. Design, optimization and pharmacokinetic evaluation of Piribedil loaded solid lipid nanoparticles dispersed in nasal in situ gelling system for effective management of Parkinson's disease

[2] Piao Zhang, et al. BMC Neurol. Hypotension and bradycardia, a serious adverse effect of piribedil, a case report and literature review

[3] A A Pilipovich, et al. Zh Nevrol Psikhiatr Im S S Korsakova. [The agonist of dopamine receptors piribedil in treatment of Parkinson's disease]

[4] Santiago Perez-Lloret, et al. CNS Drugs. Piribedil for the Treatment of Motor and Non-motor Symptoms of Parkinson Disease

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Keywords: Piribedil hydrochloride supplier, Dopamine Receptor, inhibitors, activators

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