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Pirenzepine

Cat. No. M29843

All AbMole products are for research use only, cannot be used for human consumption.

Pirenzepine Structure
Synonym:

LS 519 free base; Pirenzepin; Gastrozepin

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Quality Control & Documentation
Biological Activity

Pirenzepine (LS 519 free base) is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine shows anti-proliferative activity to cancer cells.

Chemical Information
Molecular Weight 351.4
Formula C19H21N5O2
CAS Number 28797-61-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Marius Ozenil, et al. Sci Rep. Unexpected scaffold rearrangement product of pirenzepine found in commercial samples

[2] J T Callaghan, et al. Clin Pharmacokinet. Olanzapine. Pharmacokinetic and pharmacodynamic profile

[3] A S Hale. Br J Hosp Med. Olanzapine

[4] E M Leech, et al. Ophthalmic Physiol Opt. Pirenzepine prevents form deprivation myopia in a dose dependent manner

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Keywords: Pirenzepine, LS 519 free base; Pirenzepin; Gastrozepin supplier, AChR/AChE, inhibitors, activators

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