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Pipequaline

Cat. No. M9856

All AbMole products are for research use only, cannot be used for human consumption.

Pipequaline Structure
Synonym:

PK-8165

Size Price Availability Quantity
5mg USD 70 In stock
10mg USD 100 In stock
50mg USD 350 In stock
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Quality Control & Documentation
Biological Activity

Pipequaline (PK-8165) is a partial benzodiazepine receptor agonist with anxiolytic activity. Pipequaline acts as a non-selective GABAA receptor partial agonist. Pipequaline produces dose-related decreases in motor activity. Pipequaline produces significant dose-related decreases in the number of head-dips made.

Chemical Information
Molecular Weight 316.44
Formula C22H24N2
CAS Number 77472-98-1
Solubility (25°C) DMSO 28 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] F F Eves, et al. Psychopharmacology (Berl). The effects on memory of pipequaline, alone or in combination with diazepam

[2] J Bradwejn, et al. Eur J Pharmacol. Effects of PK 8165, a partial benzodiazepine receptor agonist, on cholecystokinin-induced activation of hippocampal pyramidal neurons: a microiontophoretic study in the rat

[3] G Debonnel, et al. Neuropharmacology. Pipequaline acts as a partial agonist of benzodiazepine receptors: an electrophysiological study in the hippocampus of the rat

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Keywords: Pipequaline, PK-8165 supplier, GABA Receptor, inhibitors, activators

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