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Pindolol is a 5-HT1A/1B receptor antagonist (Ki=33nM), with roughly equal affinity for each subtype. Pindolol is a partial agonist at mouse and human β3-adrenoceptors. Pindolol also shows membrane stabilizing effects like quinidine, possibly accounting for its antiarrhythmic effects.
| Molecular Weight | 248.32 |
| Formula | C14H20N2O2 |
| CAS Number | 13523-86-9 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Francesc Artigas, et al. Pindolol augmentation of antidepressant response
[2] J S Olver, et al. Pindolol augmentation of antidepressants: a review and rationale
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