Free shipping on all orders over $ 500

Pimonidazole hydrochloride

Cat. No. M14755

All AbMole products are for research use only, cannot be used for human consumption.

Pimonidazole hydrochloride Structure
Size Price Availability Quantity
10mg USD 50 In stock
25mg USD 110 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia .

Chemical Information
Molecular Weight 290.75
CAS Number 70132-51-3
Solubility (25°C) Water 5 mg/mL (ultrasonic and warming and heat to 60°C)
Storage 2-8°C, dry, sealed
References

[1] Kristina Y Aguilera, et al. Hypoxia Studies with Pimonidazole in vivo

[2] Kristine Gulliksrud, et al. Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry

[3] C B Westbury, et al. Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride

[4] Ralph E Durand, et al. The fate of hypoxic (pimonidazole-labelled) cells in human cervix tumours undergoing chemo-radiotherapy

[5] Johannes H A M Kaanders, et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.

Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.

NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.

Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.

Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.

  Catalog
Abmole Inhibitor Catalog




Keywords: Pimonidazole hydrochloride supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.