All AbMole products are for research use only, cannot be used for human consumption.
Pifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy.
J Agric Food Chem. 2017 Mar 15;65(10):2089-2099.
10-Gingerol, a Phytochemical Derivative from “Tongling White Ginger”, Inhibits Cervical Cancer: Insights into the Molecular Mechanism and Inhibitory Targets
Pifithrin-μ purchased from AbMole
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Source | APMIS.m (2017). Figure 7. Pifithrin-μ (Abmole Bioscience Inc. Houston, TX, USA) |
| Method | Western blot | |
| Cell Lines | HeLa cells | |
| Concentrations | ||
| Incubation Time | ||
| Results | Particularly, pifithrin-μ and WZ4003 dramatically decreased 10-G-induced activation of the p53 and p-AMPK protein, respectively. |
| Molecular Weight | 181.21 |
| Formula | C8H7NO2S |
| CAS Number | 64984-31-2 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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