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Picrotin is an active compound, also is one of the composition of picrotoxin (an antagonist of GABAA receptors (GABAARs) and glycine receptors (GlyRs)). Picrotin has sensitivity for GlyRs/b> with IC50 values range from 5.2 μM to 106 μM. Picrotin can be used for the research of neurotransmission.
| Molecular Weight | 310.3 |
| Formula | C15H18O7 |
| CAS Number | 21416-53-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[1] Ping Li et al. Neuroreport. Gating effects on picrotin block of glycine receptors
[4] S N SLATER et al. Nature. Relationship between picrotin and picrotoxinin
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