All AbMole products are for research use only, cannot be used for human consumption.
Picrinine is an Akuammiline alkaloid isolated from the leaves of Alstonia Scholaris. Picrinine shows anti-inflammatory activity by inhibiting 5-lipoxygenase.
| Molecular Weight | 338.40 |
| Formula | C20H22N2O3 |
| CAS Number | 4684-32-6 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
[5] Joel M Smith, et al. Total synthesis of the akuammiline alkaloid picrinine
| Related Lipoxygenase Products |
|---|
| Malotilate
Malotilate is a hepatoprotective agent used in the treatment of liver disease. |
| Zileuton
Zileuton is an orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis with IC50 values of 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively. |
| GSK2190915
GSK2190915 (AM803), a potent FLAP inhibitor, prevents the synthesis of leukotrienes and 5-oxo-ETE, with IC50 of 76 nM for inhibition of LTB4 in human blood, provides treatment for asthma. |
| MK 886
Mk-886 (L 663536) is a potent, cellular permeable, orally active inhibitor of FLAP (IC50 at 30 nM) and leukotriene biosynthesis (IC50 at 3 nM and 1.1μM in whole white blood cells and human whole blood, respectively). Mk-886 is also a non-competitive PPARα antagonist that can induce apoptosis. |
| 2-TEDC
2-TEDC is a 5-, 12-, 15-Lipoxygenase inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
