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AZD3458 

Cat. No. M29283

All AbMole products are for research use only, cannot be used for human consumption.

AZD3458  Structure

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Quality Control & Documentation
Biological Activity

AZD3458 is a potent and remarkably selective PI3Kγ inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ, respectively.

Chemical Information
Molecular Weight 433.54
Formula C20H23N3O4S2
CAS Number 2132961-46-5
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Larissa S Carnevalli, et al. Mol Cancer Ther. Macrophage Activation Status Rather than Repolarization Is Associated with Enhanced Checkpoint Activity in Combination with PI3Kγ Inhibition

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  Catalog
Abmole Inhibitor Catalog




Keywords: AZD3458  supplier, PI3K, inhibitors, activators

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