Free shipping on all orders over $ 500

Phenytoin

Cat. No. M5875

All AbMole products are for research use only, cannot be used for human consumption.

Phenytoin Structure
Synonym:

Diphenylhydantoin; 5,5-Diphenylhydantoin

Size Price Availability Quantity
100mg USD 30 In stock
500mg USD 40 In stock
1g USD 50 In stock
5g USD 75 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin reduces breast tumour growth and metastasis in mice, and it also has antiepileptic activity. Phenytoin has been shown to activate PXR and subsequently influence the expression of PXR target genes.

Chemical Information
Molecular Weight 252.27
Formula C15H12N2O2
CAS Number 57-41-0
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Franco V, et al. Expert Opin Drug Metab Toxicol. CYP2C9 polymorphisms and phenytoin metabolism: implications for adverse effects.

Related Sodium Channel Products
Riluzole

Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

A-803467

A-803467 is a potent and selective Nav1.8 sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50 = 140 nM).

Oxcarbazepine

Oxcarbazepine is an anticonvulsant and mood-stabilizing compound.

Ambroxol hydrochloride

AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM.

Camostat mesylate

Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

  Catalog
Abmole Inhibitor Catalog




Keywords: Phenytoin, Diphenylhydantoin; 5,5-Diphenylhydantoin supplier, Sodium Channel, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.