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Phenazopyridine HCl is a competitive SARM1 inhibitor as well as a TRPM8 antagonist with an IC50 for SARM1 inhibition of 145 μM. It has local anesthetic/analgesic activity and can be used in studies related to traumatic brain injury, peripheral neuropathy, and neurodegenerative diseases.
| Molecular Weight | 249.7 |
| Formula | C11H11N5.HCl |
| CAS Number | 136-40-3 |
| Solubility (25°C) | DMSO 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Phenazopyridine
[2] National Toxicology Program. Phenazopyridine hydrochloride
[3] Kaye K Gaines. Phenazopyridine hydrochloride: the use and abuse of an old standby for UTI
[4] A J Eisinger, et al. Phenazopyridine-hydrochloride haemolysis
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