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PF-514273 is a highly selective CB1 antagonist. The Ki for binding to CB1 and CB2 receptors is 1 nM and 10 mM, respectively. PF-514273 inhibits food intake and weight gain in rodents.
| Molecular Weight | 452.28 |
| Formula | C21H17Cl2F2N3O2 |
| CAS Number | 851728-60-4 |
| Solubility (25°C) | DMSO: ≥5 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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